The AqueaTether™ platform is a group of novel linker- and polymer-related technologies upon which hybrid (conjugated) chemical entities can be developed with improved therapeutic performance:
- Additionally, the AqueaTether™ platform contains an array of active AqT™ molecules linked
to cytotoxic payloads with greatly improved water solubility for use in antibody-drug
conjugation. The platform is suitable for both established and novel antibodies to produce
highly active ADCs with minimal aggregation and precipitation.
Intellectual Properties Position: extensive patent protection for the composition matter of AqT™ molecules and their conjugates (WO2013/012961A2, issued patents: US14/210,121, US14/156,224).